Faculty Profile- Anirudha Giri

Research Profile

In recent times the amphibian are experiencing an unprecedented population decline on a global scale. As we are yet to understand the exact cause of such decline, it would be premature to assume that such a phenomenon is restricted to amphibians only and other species are not affected. Although habitat loss and infectious diseases are believed to be the major causes of this catastrophic phenomenon, the contribution of environmental contaminants as a causative factor is increasingly gaining ground. I am particularly interested to know how the emerging pollutants of concern could affect the physiology, development, reproduction, genetic and life history traits of amphibians. The findings would help predict how contaminants could shape the biodiversity in future and devise methods for their conservation. With a young team of researchers and financial assistance from DBT and UGC, I am exploring the possibility of obtaining bioactive molecules from amphibians for possible therapeutic application as well as the possibility of using amphibians as robust indicator of contaminant exposure in aquatic habitats. In addition, my research group is constantly working on assessment of the adverse effect of contaminant exposure due to occupational exposure or to life style factors, on vital health parameters using epidemiological approach as well as laboratory validation in different experimental model organisms.

Selected publications:

• Singha U, Pandey N, Boro F & Biswas S. (2014). Sodium arsenite induced changes in survival, growth, metamorphosis and genotoxicity in the Indian
  cricket frog (Rana limnocharis). Chemosphere, 112: 333-339. [IF 3.867]. [Citation: new publication].
• Kausar A, Giri S & Roy P (2014). Changes in buccal micronucleus cytome parameters associated with smokeless tobacco and pesticide exposure
  among female tea garden workers of Assam, India. Int J Hyg Environ Health, 217: 169– 175. [IF 3.331]. [Citation: new publication].
• Das Roy L, Giri S & Singh S (2013). Effects of radiation and vitamin C treatment on metronidazole genotoxicity in mice. Mutat Res, 753: 65– 71.
  [IF 2.716]. [Citation 01].
• Yadav SS, Giri S, Singha U & Boro F (2013). Toxic and genotoxic effects of Roundup on tadpoles of the Indian skittering frog (Euflictis
  cyanophlyctis) in the presence and absence of predator stress. Aquat Toxicol, 132-133: 1–8. [IF 3.948]. [Citation 16].
• Yadav SS, Giri S & Sharma GD (2012). Effect of predator stress and malathion on tadpoles of Indian skittering frog. Aquat Toxicol, 106–107: 157 –
  163. [IF 3.948]. [Citation 06].
• Giri A, Giri S & Sharma GD (2011). Malathion and fenvalerate: Induction of micronuclei in the bone marrow cells of mice. Environ Mol Mutag, 52:607-
  613. [IF 2.553]. [Citation 06].
• Mazumdar M & Giri S (2011). Effects of quercetin and mitomycin –C induced genotoxicity: analysis of micronucleus and chromosomal aberration in
  vivo. Mutat Res, 721: 147–152. [IF 2.716]. [Citation 11].
• Kausar A, Giri S, Mazumdar M, Roy P & Dhar P (2009). Micronucleus and other nuclear abnormalities among betel quid chewers with or without
  sadagura, a unique smokeless tobacco preparation, in a population from North East India. Mutat Res, 677: 72–75. [IF 2.716]. [Citation 15].
  Giri S, Sharma GD & Prasad SB (2003). Induction of sister chromatid exchanges by cypermethrin and carbosulfan in the bone marrow cells of mice
  in vivo. Mutagenesis, 18(1): 53 – 58. [IF 3.798]. [Citation 47].
• Giri S, Prasad SB & Sharma GD (2002). Genotoxic effects of malathion, an organophosphorous insecticide, using three mammalian bioassays in
  vivo. Mutat Res, 514: 223 – 231. [IF 2.716]. [Citation 92].
• Giri S, Sharma GD & Prasad SB (2002). Mutagenic effects of carbosulfan, a carbamate pesticide. Mutat Res, 519: 75 – 82. [IF 2.716]. [Citation 39].
  Giri S, Sharma GD & Prasad SB (2002). Fenvalerate induced chromosome aberrations and sister chromatid exchanges in the bone marrow cells of
  mice in vivo. Mutat Res, 520: 125 – 132. [IF 2.716]. [Citation 36].
• Khynriam D & Prasad SB (1998). Vitamin C mediated protection on cisplatin-induced mutagenicity in mice. Mutat Res, 421:139–148. [IF
  2.716]. [Citation 79].
• Prasad SB (1994). Antitumor activity of cisplatin against murine ascites Dalton’s lymphoma. IndJ Exp Biol, 32: 155 – 162. [IF 1.3]. [Citation 134].
  Prasad SB (1992). Use of subtherapeutic dose of cisplatin and vitamin C against murine Dalton’s lymphoma. Pol J Pharmacol Pharm*
  , 44: 383 – 391.
• [IF 2.402] (*Presently Pharmacological Reports) [Citation 12]